About us

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for forty years.

We have four divisions:

(1) Oncology and Haematology (2) Ophthalmology (3) International Wholesale


Products

Buy diacomit

Buy diacomit

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Buy stiripentol

Buy stiripentol

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Diacomit (Stiripentol)

Diacomit (Stiripentol)

Diacomit (Stiripentol) belongs to a group of medicines called antiepileptics. Diacomit (Stiripentol) is indicated for use in conjunction with clobaza...

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Diacomit England

Diacomit England

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Diacomit supplier

Diacomit supplier

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Diacomit UK

Diacomit UK

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Obtain diacomit

Obtain diacomit

Ophthalmic medicine is one of our key divisions. We work with most of the principal manufacturers of ophthalmic products, together with some niche man...

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Obtain diacomit

Obtain diacomit

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

Read More
Obtain stiripentol

Obtain stiripentol

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

Read More
Purchase diacomit

Purchase diacomit

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

Read More
Purchase stiripentol

Purchase stiripentol

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

Read More
Stiripentol

Stiripentol

We are distributors for Biocodex (France) for their range of Diacomit (Stiripentol):- Diacomit (Stiripentol) 250mg x 60 capsules Diacomit (Stiripent...

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Stiripentol supplier

Stiripentol supplier

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Stiripentol UK

Stiripentol UK

Alan Pharmaceuticals is a British company that has been providing pharmaceutical solutions for over thirty years.

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Talidex

Talidex

We manufacture Thalidomide under our brand name Talidex. It is available in blister packs of 30 tablets and in three different strengths: » 30 x Tali...

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15 Products

News

Iluvien

Iluvien

Alimera Sciences Inc. (USA) has appointed Alan Pharmaceuticals as exclusive distributor of ILUVIEN® for the UK private market. Alan Pharmaceuticals also welcomes enquiries for ILUVIEN® from outside the UK.

ILUVIEN® is now available for immediate supply.

LICENSED INDICATION

ILUVIEN® is indicated for the treatment of vision impairment associated with chronic diabetic macular oedema (DMO) considered insufficiently responsive to available therapies. There are believed to be over 180,000 patients within the UK, France and Germany who suffer with clinically significant DMO.

PRODUCT SPECIFICATIONS

ILUVIEN® 190 micrograms intravitreal implant in applicator is manufactured by Alimera Sciences. The implant delivers 190mcgs of fluocinolone acetonide (FAc).

The implant is a light brown coloured cylinder approximately 3.5mm in length and 0.37mm in diameter (see illustration). Each implant comes pre-loaded in a "use once and discard" applicator and is administered via a direct intravitreal injection using a 25-gauge needle.

ILUVIEN® provides 36 months of consistent fluocinolone acetonide (FAc) from a single micro implant. ILUVIEN® has the potential to provide chronic DMO patients improved visual acuity at 36 months compared with baseline with one sustained-release micro implant (Campochario PA, Brown DM et al. Ophthalmology 2012; 119: 2125-2131).

Only patients who have been insufficiently responsive to prior treatment with laser photocoagulation or other available therapies for DMO should be treated with ILUVIEN®.

POSOLOGY AND METHOD OF ADMINISTRATION

The recommended dose is one ILUVIEN® implant in the affected eye. Administration in both eyes concurrently is not recommended.

Treatment with ILUVIEN® is for intravitreal use only and should be administered by an ophthalmologist experienced in intravitreal injections. The implant insertion should be carried out under controlled aseptic conditions, which include the use of sterile gloves, a sterile drape, and a sterile eyelid speculum (or equivalent). Adequate anaesthesia and a broad-spectrum microbicide should be given prior to the insertion. Further information on administration can be found in the ILUVIEN® pack insert.

PHARMACODYNAMIC PROPERTIES

The efficacy of ILUVIEN® was assessed in two randomised, multicentre, double-masked, parallel studies enrolling subjects with DMO who had previously been treated with laser photocoagulation at least once, each involving three years of follow-up.

The primary efficacy endpoint in both trials was the proportion of subjects whose vision improved by 15 letters or greater after 24 months.

In each of these trials, the primary endpoint was met for ILUVIEN® (see left panel in the Figure below).

When efficacy was assessed as a function of duration of disease, those subjects with a duration of DMO greater than the median (=3 years) had a significant beneficial response to ILUVIEN®, whilst those with shorter duration DMO did not show an additional benefit over control treatment with regard to visual improvement (see right panel in the Figure below).

CONTRAINDICATIONS

ILUVIEN® is contraindicated in the presence of pre-existing glaucoma or active or suspected ocular or peri-ocular infection including most viral diseases of the cornea and conjunctiva, including active epithelial herpes simplex keratitis, vaccinia, varicella, mycobacterial infections and fungal diseases.

ADVERSE EVENTS

Uncommon (≥1/1000 to ≥1/100) – endophthalmitis, headache

Common (≥1/100 to ≥1/10) – glaucoma, trabeculectomy, eye pain

Very Common(≥1/10) – cataract, increased IOP, floaters (myodesopsia)

SHELF LIFE

Two years

STORAGE CONDITIONS

Store below 30°C. Do not refrigerate or re-freeze.

MARKETING AUTHORISATION HOLDER

Alimera Sciences Limited, Centaur House, Ancells Business Park, Ancells Road, Fleet, GU51 2UJ UK

Click here for more information on Iluvien

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